CETRORELIX ACETATE

CAS 145672-81-7 MFCD08459466

化学结构图

145672-81-7
SMILES:

化学属性

Mol. FormulaC70H92ClN17O14· xC2H4O2
Mol. Weight1431.04 (free base basis)

别名和识别编码

Chemical NameCetrorelix acetate
Synonym NS-75A Cetrotide N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide acetic acid salt SB-75 Cetrotide N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide acetic acid salt NS-75A SB-75
MDL NumberMFCD08459466
CAS Number145672-81-7
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Luteinizing Hormone (LH), Merck, Pituitary Hormones
  • {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Cytokines, Growth Factors and Hormones, Hormones, Luteinizing Hormone (LH), Pituitary Hormones, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Gründker C et al. Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer. Reprod Biol Endocrinol. 2003 Oct 7;1:65.
  • 1. Roth, C.L., et al., Different effects of agonistic vs. antagonistic GnRH-analogues (triptorelin vs. cetrorelix) on bone modeling and remodeling in peripubertal female rats Exp. Clin. Endocrinol. Diabetes 113 , 451-456, (2005)
  • Kanaho, Y., et al., Neurotrophic effect of gonadotropin-releasing hormone on neurite extension and neuronal migration of embryonic gonadotropin-releasing hormone neurons in chick olfactory nerve bundle culture J. Neurosci. Res. 87 , 2237 - 2244, (2009) 摘要
  • Merck 14 ,2026
  • Telegdy, G., et al., Effects of the LHRH antagonist Cetrorelix on the brain function in mice Neuropeptides 43 , 229 234, (2009)
  • Ziegler, CG., et al., Expression of neuropeptide hormone receptors in human adrenal tumors and cell lines: antiproliferative effects of peptide analogues Proc. Natl. Acad. Sci. U. S. A. , (200

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P308+P313
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
Signal word Danger Warning
Hazard statements
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
Risk Statements
  • R60 May impair fertility 可能降低生殖能力
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Pituitary Hormones - Hormones
  7. Luteinizing Hormone (LH) - Pituitary Hormones
  1. Medical Research Areas
  2. GPCR & G Protein
  3. GnRH Receptor  (促性腺激素释放激素受体)

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