喹硫平硫氧化物/喹硫平亚砜 喹硫平硫氧化物/喹硫平亚砜

CAS 329216-63-9 MFCD08460237

化学结构图

329216-63-9
SMILES: OCCOCCN1CCN(CC1)C1=NC2C=CC=CC=2S(=O)C2C=CC=CC1=2

化学属性

Mol. FormulaC21H25N3O3S
Mol. Weight399.51

别名和识别编码

Chemical NameQuetiapine Sulfoxide
CAS Number329216-63-9
Synonym 2-[2-[4-(5-Oxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]ethanol
Chemical Name Translation喹硫平硫氧化物/喹硫平亚砜
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分类

  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • A metabolite of Quetiapine, which is used as an antipsychotic.

相关文献及参考

  • [2]. Cross AJ, et al. Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models. Br J Pharmacol. 2016 Jan;173(1):155-66.
  • Onrust, S., et al.: CNS Drugs, 15, 329
  • [1]. Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5(6):528-537.
  • [1]. Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5(6):528-537.
  • [2]. Cross AJ, et al. Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models. Br J Pharmacol. 2016 Jan;173(1):155-66.

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Drug Metabolite  (药物代谢物)

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