4-(4'-BENZAMIDOANILINO)-6,7-DIMETHOXYQUINAZOLINE HYDROCHLORIDE N-[4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenyl]benzamide 盐酸盐

CAS 179247-42-8 MFCD09265252

化学结构图

179247-42-8
SMILES: Cl.COC1=CC2N=CN=C(NC3C=CC(=CC=3)NC(=O)C3C=CC=CC=3)C=2C=C1OC

化学属性

Mol. FormulaC23H20N4O3· HCl
Mol. Weight436.89

别名和识别编码

Chemical NameN-[4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenyl]benzamide hydrochloride
Synonym 4-(4′-Benzamidoanilino)-6,7-dimethoxyquinazoline 盐酸盐 Aurora Kinase Inhibitor II Aurora Kinase Inhibitor II 4-(4'-Benzamidoanilino)-6,7-dimethoxyquinazoline 盐酸盐 Aurora Kinase Inhibitor II 4-(4'-Benzamidoanilino)-6,7-dimethoxyquinazoline 盐酸盐 N-[4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenyl]benzamide 盐酸盐
MDL NumberMFCD09265252
PubChem Substance ID24724466
CAS Number179247-42-8
Chemical Name TranslationN-[4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenyl]benzamide 盐酸盐
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分类

  • {SA} Approved Therapeutics/Drug Candidates, AstraZeneca,
  • Approved Therapeutics/Drug Candidates, AstraZeneca, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DIG-DY, Kinase/Phosphatase Biology, Protein Kinases (PK), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
  • {SNA} Approved Therapeutics/Drug Candidates, AstraZeneca, Bioactive Small Molecule Alphabetical Index, DIG-DY, Diversification Ready Pharma-Developed Compounds, Kinase/Phosphatase Biology, Protein Kinases (PK), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • Heron, N.M., et al. , SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors Bioorg. Med. Chem. Lett. 16 , 1320-1323, (2006) 摘要

安全信息

GHS Symbol
WGK Germany3
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
  • R22 Harmful if swallowed 吞咽有害

系列性分类


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