FTY720 (S)-Phosphate

CAS 402616-26-6 MFCD09840646

化学结构图

402616-26-6
SMILES: CCCCCCCCC1=CC=C(CC[C@@](N)(COP(O)(O)=O)CO)C=C1

化学属性

Mol. FormulaC19H34NO5P
Mol. Weight387.4507

别名和识别编码

Chemical NameFTY720 (S)-Phosphate
CAS Number402616-26-6
Synonym 2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester (S)-FTY720-P
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分类

  • Inhibitors
  • Metabolites & Impurities

产品应用

  • FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-

相关文献及参考

  • [2]. Lingling Jia, et al. Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells. Front Immunol. 2017 Oct 19;8:1345.
  • Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002),
  • Chiba, K., et al.: J. Immunol., 160, 5037 (1998),
  • [1]. Wang L, et al. FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury. Crit Care Med. 2014 Mar;42(3):e189-99.
  • [1]. Wang L, et al. FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury. Crit Care Med. 2014 Mar;42(3):e189-99.
  • [2]. Lingling Jia, et al. Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells. Front Immunol. 201

系列性分类


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