8-chloro-6,11-dihydro-11-(4-piperdinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 8-氯-6,11-二氢-11-(4-哌啶烯基)-5H-苯并[5,6]环庚基[1,2-b]吡啶

CAS 100643-71-8 MFCD10567131

化学结构图

100643-71-8
SMILES: Clc1ccc2c(c1)CCc1cccnc1C2=C1CCNCC1

化学属性

Mol. FormulaC19H19ClN2
Mol. Weight311

别名和识别编码

Chemical Name8-chloro-6,11-dihydro-11-(4-piperdinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Beilstein Registry Number4263164
Chemical Name Translation8-氯-6,11-二氢-11-(4-哌啶烯基)-5H-苯并[5,6]环庚基[1,2-b]吡啶
LabNetwork Molecule IDLN00003637
MDL NumberMFCD00871949
CAS Number100643-71-8
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相关文献及参考

  • [2]. Schroeder, J.T., et al., Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy, 2001. 31(9): p. 1369-77.
  • [3]. McClellan K, et al. Desloratadine. Drugs. 2001;61(6):789-797.
  • [4]. Anthes, J.C., et al., Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor. Eur J Pharmacol, 2002. 449(3): p. 229-37.
  • [1]. Geha, R.S. and E.O. Meltzer, Desloratadine: A new, nonsedating, oral antihistamine. J Allergy Clin Immunol, 2001. 107(4): p. 751-62.
  • [1]. Geha, R.S. and E.O. Meltzer, Desloratadine: A new, nonsedating, oral antihistamine. J Allergy Clin Immunol, 2001. 107(4): p. 751-62.
  • [2]. Schroeder, J.T., et al., Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy, 2001. 31(9): p. 1369-77.
  • [3]. McClellan K, et al. Desloratadine. Drugs. 2001;61(6):789-797.
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安全信息

GHS Symbol
UN Number 3077
Hazard Codes 9
Signal word Warning
WGK Germany3
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P301+P312
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSDE8011000
Packing GroupIII

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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