Ro 61-8048 3,4-二甲氧基-N-(4-(3-硝基苯基)噻唑-2-基)苯磺酰胺

CAS 199666-03-0 MFCD11040807

化学结构图

199666-03-0
SMILES: COc1ccc(S(=O)(=O)Nc2nc(-c3cccc([N+](=O)[O-])c3)cs2)cc1OC

化学属性

Mol. FormulaC17H15N3O6S2
Mol. Weight421.45

别名和识别编码

Chemical NameRo 61-8048
Synonym 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-benzenesulfonamide 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-benzenesulfonamide 3,4-Dimethoxy-N-[4-(3-nitrophenyl)thiazol-2-yl]benzenesulfonamide Ro-61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)thiazol-2-yl]benzenesulfonamide Ro 61-8048 Ro-61-8048 Ro-61-8048 sulfonamide
MDL NumberMFCD11040807
CAS Number199666-03-0
PubChem Substance ID5282337
Chemical Name Translation3,4-二甲氧基-N-(4-(3-硝基苯基)噻唑-2-基)苯磺酰胺
InChIInChI=1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Alzheimer's Disease, Assays/Reagents for Alzheimer's Disease Research, Bioactive Small Molecule Alphabetical Index, Neurobiology, Neuroscience, Products for Neurodegenerative Disease Research, R, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Alzheimer′s Disease, Assays/Reagents for Alzheimer′s Disease Research, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Products for Neurodegenerative Disease Research, R

相关文献及参考

  • Rodgers J, Stone TW, Barrett MP, Bradley B, Kennedy PG., Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. Brain pt 5 , 1259-67, (2009)
  • Hamann M, Sander SE, Richter A., Effects of the kynurenine 3-hydroxylase inhibitor Ro 61-8048 after intrastriatal injections on the severity of dystonia in the dt sz mutant. Eur. J. Pharmacol. 1-3 , 156-9, (2008)
  • Cozzi A, Carpenedo R, Moroni F., Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia. J. Cereb. Blood Flow Metab. 7 , 771-7, (1999)

安全信息

GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P305+P351+P338
  • P330 Rinse mouth. 漱口
  • P337+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Hazard Codes T
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R36 Irritating to eyes 刺激眼睛

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurobiology - Neuroscience
  6. Products for Neurodegenerative Disease Research - Neurobiology
  7. Alzheimer′s Disease - Products for Neurodegenerative Disease Research
  8. Assays/Reagents for Alzheimer′s Disease Research - Alzheimer′s Disease

相关产品推荐