2-(Morpholinomethyl)-5-((5-((7-(Trifluoromethyl)Quinolin-4-Yl)Thio)Pentyl)Oxy)-4H-Pyran-4-One Dihydrochloride 2-(吗啉-4-基甲基)-5-((5-((7-(三氟甲基)喹啉-4-基)硫基)戊基)氧基)-4H-吡喃-4-酮二盐酸盐

CAS 754240-09-0 MFCD11114384

化学结构图

754240-09-0
SMILES: Cl.Cl.O=C1C=C(CN2CCOCC2)OC=C1OCCCCCSC1=CC=NC2C=C(C=CC=21)C(F)(F)F

化学属性

Mol. FormulaC25H29Cl2F3N2O4S
Mol. Weight581

别名和识别编码

Chemical Name2-(Morpholinomethyl)-5-((5-((7-(Trifluoromethyl)Quinolin-4-Yl)Thio)Pentyl)Oxy)-4H-Pyran-4-One Dihydrochloride
Synonym 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride EHT 1864
MDL NumberMFCD11114384
PubChem Substance ID329799014
CAS Number754240-09-0
Chemical Name Translation2-(吗啉-4-基甲基)-5-((5-((7-(三氟甲基)喹啉-4-基)硫基)戊基)氧基)-4H-吡喃-4-酮二盐酸盐
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分类

  • {SNA} Bioactive Small Molecules, Cell Biology, E
  • {SNA} Bioactive Small Molecule Alphabetical Index, E, 生物活性小分子, 细胞生物学

相关文献及参考

  • [2]. Shutes A, et al. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. J Biol Chem. 2007 Dec 7;282(49):35666-78.
  • [3]. Onesto C, et al. Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. Methods Enzymol. 2008;439:111-29.
  • [1]. Desire L, et al. RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo. J Biol Chem. 2005 Nov 11;280(45):37516-25.
  • [1]. Desire L, et al. RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo. J Biol Chem. 2005 Nov 11;280(45):37516-25.
  • [2]. Shutes A, et al. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. J Biol Chem. 2007 Dec 7;282(49):35666-78.
  • [3]. Onesto C, et al. Characterization of EHT 1864, a n

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. E - Bioactive Small Molecules
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Ras  (Ras蛋白)

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