Vicriviroc Maleate

CAS 599179-03-0 MFCD11973900

化学结构图

599179-03-0
SMILES: CC1(CCN(CC1)C(=O)C1C(C)=NC=NC=1C)N1CCN([C@@H](COC)C2C=CC(=CC=2)C(F)(F)F)[C@@H](C)C1.OC(=O)/C=C/C(O)=O

化学属性

Mol. FormulaC28H38F3N5O2
Mol. Weight534

别名和识别编码

Chemical NameVicriviroc Maleate
Chemical Name Translation
MDL Number
CAS Number599179-03-0
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相关文献及参考

  • [2]. Strizki JM, et al. Discovery and characterization of vicriviroc (SCH 417690), a CCR5 antagonist with potent activity against human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2005 Dec;49(12):4911-9.
  • [1]. Tagat JR, et al. Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. J Med Chem. 2004 May 6;47(10):2405-8.
  • [1]. Tagat JR, et al. Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. J Med Chem. 2004 May 6;47(10):2405-8.
  • [2]. Strizki JM, et a

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. CCR  (趋化因子受体)

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