(1-Cyano-2-Ethoxy-2-Oxoethylidenaminooxy)Dimethylamino-Morpholino-Carbenium Hexafluorophosphate (2-肟基-氰基乙酸乙酯)-N,N-二甲基-吗啉基脲六氟磷酸酯

CAS 1075198-30-9 MFCD11975052

化学结构图

1075198-30-9
SMILES: CCOC(=O)/C(/C#N)=N\OC(N1CCOCC1)=[N+](C)C.F[P-](F)(F)(F)(F)F

化学属性

Mol. FormulaC12H19F6N4O4P
Mol. Weight428.27
Melting Point151.4 -152.9
TSCANo

别名和识别编码

Chemical Name(1-Cyano-2-Ethoxy-2-Oxoethylidenaminooxy)Dimethylamino-Morpholino-Carbenium Hexafluorophosphate
Synonym (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate (1-氰基-2-乙氧基-2-氧亚乙基氨基氧)二甲氨基-吗啉基-碳鎓六氟磷酸盐 COMU COMU®
MDL NumberMFCD11975052
CAS Number1075198-30-9
Chemical Name Translation(2-肟基-氰基乙酸乙酯)-N,N-二甲基-吗啉基脲六氟磷酸酯
Beilstein Registry Number19762713
PubChem Substance ID329763117
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分类

  • {SNA} 12 Principles Aligned Products, Chemical Biology, Chemical Synthesis, Coupling, Greener Alternative Products, Peptide Chemistry, Peptide Coupling, Phosphonium/Uronium/Formamidinium, Synthetic Reagents
  • {SNA} Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling, Phosphonium/Uronium/Formamidinium, Synthetic Reagents

相关文献及参考

  • 1. El-Faham, A.; et al., COMU: A Safer and More Effective Replacement for Benzotriazole-Based Uronium Coupling Reagents Chem. Eur. J. 15 , 9404, (2009)

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P302+P352
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition Air & Moisture Sensitive
Hazard Codes Xi

系列性分类


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