2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid 2-环戊基-4-(5-苯基-1H-吡咯并[2,3-b]吡啶-3-基)苯甲酸

CAS 890842-28-1 MFCD12828779

化学结构图

890842-28-1
SMILES: OC(=O)C1=CC=C(C=C1C1CCCC1)C1=CNC2=NC=C(C=C12)C1C=CC=CC=1

化学属性

Mol. FormulaC25H22N2O2
Mol. Weight382.461

别名和识别编码

Chemical Name2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid
Chemical Name Translation2-环戊基-4-(5-苯基-1H-吡咯并[2,3-b]吡啶-3-基)苯甲酸
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相关文献及参考

  • [2]. Mansley MK, et al. Effects of nominally selective inhibitors of the kinases PI3K, SGK1 and PKB on the insulin-dependent control of epithelial Na+ absorption. Br J Pharmacol. 2010 Oct;161(3):571-88.
  • [3]. Peng HY, et al. Spinal SGK1/GRASP-1/Rab4 is involved in complete Freund's adjuvant-induced inflammatory pain via regulating dorsal horn GluR1-containing AMPA receptor trafficking in rats. Pain. 2012 Dec;153(12):2380-92.
  • [4]. Peng HY, et al. Spinal serum-inducible and glucocorticoid-inducible kinase 1 mediates neuropathic pain via kalirin and downstream PSD-95-dependent NR2B phosphorylation in rats. J Neurosci. 2013 Mar 20;33(12):5227-40.
  • [5]. Alamares-Sapuay JG, et al. Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus. J Virol. 2013 May;87(10):6020-6.
  • [1]. Sherk AB, et al. Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and it

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. SGK  (血清和糖皮质激素调节蛋白激酶)

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