Elesclomol N'1,N'3-二甲基-N'1,N'3-二(苯基硫代羰基)丙二酰肼

CAS 488832-69-5 MFCD12911784

化学结构图

488832-69-5
SMILES: CN(NC(=O)CC(=O)NN(C)C(=S)C1C=CC=CC=1)C(=S)C1C=CC=CC=1

化学属性

Mol. FormulaC19H20N4O2S2
Mol. Weight400.525

别名和识别编码

Chemical NameElesclomol
Chemical Name TranslationN'1,N'3-二甲基-N'1,N'3-二(苯基硫代羰基)丙二酰肼
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相关文献及参考

  • [2]. Liam M Guthrie, et al. Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice. Science. 2020 May 8;368(6491):620-625.
  • [3]. Bair JS, et al. Chemistry and biology of deoxynyboquinone, a potent inducer of cancer cell death. J Am Chem Soc. 2010 Apr 21;132(15):5469-7
  • [1]. Kirshner JR, et al. Elesclomol induces cancer cell apoptosis through oxidative stress. Mol Cancer Ther. 2008 Aug;7(8):2319-27.
  • [1]. Kirshner JR, et al. Elesclomol induces cancer cell apoptosis through oxidative stress. Mol Cancer Ther. 2008 Aug;7(8):2319-27.
  • [2]. Liam M Guthrie, et al. Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice. Science. 2020 May 8;368(6491):620-625.
  • [3]. Bair JS, et al. Chemistry and biology of deoxynyboquinone, a potent inducer of cancer cell death. J Am Chem Soc. 2010 Apr 21;132(15):5469-7

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Reactive Oxygen Species  (活性氧)

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