HS014

CAS 207678-81-7 MFCD12912469

化学结构图

207678-81-7
SMILES: CC(=O)N[C@H]1CSSC[C@@H](NC(=O)CNC(=O)[C@H](CC2=CNC3C=CC=CC2=3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC2C=C3C=CC=CC3=CC=2)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@H](CCC(O)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(N)=O

化学属性

Mol. FormulaC71H94N20O17S2
Mol. Weight1563.78

别名和识别编码

Chemical NameHS014
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相关文献及参考

  • [2]. Ercil NE, et al. HS014, a selective melanocortin-4 (MC4) receptor antagonist, modulates the behavioral effects of morphine in mice. Psychopharmacology (Berl). 2005;180(2):279-285.
  • [3]. Kask A, et al. Selective antagonist for the melanocortin 4 receptor (HS014) increases food intake in free-feeding rats. Biochem Biophys Res Commun. 1998;245(1):90-93.
  • [1]. Schiöth HB,et al. Discovery of novel melanocortin4 receptor selective MSH analogues. Br J Pharmacol. 1998;124(1):75-82.
  • [1]. Schiöth HB,et al. Discovery of novel melanocortin4 receptor selective MSH analogues. Br J Pharmacol. 1998;124(1):75-82.
  • [2]. Ercil NE, et al. HS014, a selective melanocortin-4 (MC4) receptor antagonist, modulates the behavioral effects of morphine in mice. Psychopharmacology (Berl). 2005;180(2):279-285.
  • [3]. Kask A, et al. Selective antagonist for the melanocortin 4 receptor (HS014) increases food intake in free-feeding rats. Biochem Biophys Res Commun. 1998

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Melanocortin Receptor  (黑皮质素受体)

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