Azd2281(Olaparib) 奥拉帕尼
CAS 763113-22-0 MFCD13185161
化学结构图
SMILES: O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCN(C(=O)C2CC2)CC1
化学属性
| Mol. Formula | C24H23FN4O3 |
|---|---|
| Mol. Weight | 434 |
别名和识别编码
| Chemical Name | Azd2281(Olaparib) |
|---|---|
| CAS Number | 763113-22-0 |
| Alfabeta Name | CYCLOPROPYLCARBONYLDIHYDROOXOPHTHALAZINYLMETHYLFLUOROBENZOYLPIPERAZINE 14534412[[]](())-----------, |
| MDL Number | MFCD13185161 |
| Synonym | 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone AZD 2281 KU 0059436 KU 59436 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)meth |
| Chemical Name Translation | 奥拉帕尼 |
| LabNetwork Molecule ID | LN00160199 |
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分类
- Aromatics
- Heterocycles
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
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相关文献及参考
- Weston, V.J. et al.: Blood, 116, 4578 (2010); Senra, J.M. et al.: Mol. Cancer Therap., 10, 1949 (2011); Schaefer, N.G. et al.: Nuc. Med. Comm., 32, 1046 (2011);
安全信息
GHS Symbol
- S000924/25
- S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
- R22 Harmful if swallowed 吞咽有害
- R36 Irritating to eyes 刺激眼睛
- R37 Irritating to respiratory system 刺激呼吸道
- R38 Irritating to skin 刺激皮肤
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P301+P310
- P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
- P330 Rinse mouth. 漱口
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