N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine N,N'-二-2-吡啶基-1,4-苯二甲胺
CAS 55778-02-4 MFCD18086914
化学结构图
SMILES: C(NC1=CC=CC=N1)C1C=CC(CNC2C=CC=CN=2)=CC=1
化学属性
| Mol. Weight | 290.36 |
|---|---|
| Mol. Formula | C18H18N4 |
别名和识别编码
| Synonym | N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine |
|---|---|
| MDL Number | MFCD18086914 |
| CAS Number | 55778-02-4 |
| Chemical Name | N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine |
| Chemical Name Translation | N,N'-二-2-吡啶基-1,4-苯二甲胺 |
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分类
- {SNA} Bioactive Small Molecule Alphabetical Index, Chemokine Inhibitors, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, W, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemokine Inhibitors, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, W
相关文献及参考
- Zhu A, Zhan W, Liang Z, Yoon Y, Yang H, Grossniklaus HE, et al., Dipyrimidine Amines: A Novel Class of Chemokine Receptor Type 4 Antagonists with High Specificity. J. Med. Chem. , (2010)
- Zhan W, Liang Z, Zhu A, Kurtkaya S, Shim H, Snyder JP, Liotta DC., Discovery of small molecule CXCR4 antagonists. J. Med. Chem. 23 , 5655-64, (2007) 摘要
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
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