L 748337 hydrate

CAS N/A MFCD20134197

化学结构图

N/A
SMILES:

化学属性

Mol. Weight497.61 (anhydrous basis)
Mol. FormulaC26H31N3O5S · xH2O

别名和识别编码

Synonym N-(3-{3-[2-(4-Benzenesulfonylamino-phenyl)-ethylamino]-(2S)-2-hydroxy-propoxy}-benzyl)-acetamide hydrate; Acetamide, N-[[3-[(2S)-2-hydroxy-3-[[2-[4-[(phenylsulfonyl)amino]phenyl]ethyl]amino]propoxy]phenyl]methyl] hydrate L 748337 hydrate
MDL NumberMFCD20134197
Chemical NameL 748337 hydrate
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分类

  • {SNA} Adrenergics, Adrenergics - Antagonists, Antagonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, L, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators,

相关文献及参考

  • Sarma DN, Banwait K, Basak A, DiMarino AJ, Rattan S., Inhibitory effect of beta3-adrenoceptor agonist in lower esophageal sphincter smooth muscle: in vitro studies. J. Pharmacol. Exp. Ther. 1 , 48-55, (2003)
  • Skeberdis VA, Gendviliene V, Zablockaite D, Treinys R, Macianskiene R, Bogdelis A, et al., beta3-adrenergic receptor activation increases human atrial tissue contractility and stimulates the L-type Ca2+ current. J. Clin. Invest. 9 , 3219-27, (2008) 摘要
  • Candelore MR, Deng L, Tota L, Guan XM, Amend A, Liu Y, Newbold R, Cascieri MA, Weber AE., Potent and selective human beta(3)-adrenergic receptor antagonists. J. Pharmacol. Exp. Ther. 2 , 649-55, (1999)

安全信息

WGK Germany3

系列性分类


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