2,2,2-Trichloroethyl carbamate

CAS 107-69-7 MFCD01738999

化学结构图

107-69-7
SMILES: NC(=O)OCC(Cl)(Cl)Cl

化学属性

Mol. FormulaC3H4Cl3NO2
Mol. Weight192.43

别名和识别编码

Chemical Name2,2,2-Trichloroethyl carbamate
Chemicalbook IDCB5883794
Wiswesser Line NotationZVO1XGGG
Synonym Trichloroethyl carbamate Ethanol, 2,2,2-trichloro-, carbamate Voluntal Carbamic acid, 2,2,2-trichloroethyl ester Trichlorourethane
CAS Number107-69-7
Beilstein Registry Number1762058
PubChem Substance ID7883
InChIInChI=1S/C3H4Cl3NO2/c4-3(5,6)1-9-2(7)8/h1H2,(H2,7,8)
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安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3250 mg/kg/13W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   8,99,1947

RTECSFD1750000
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   LDTU** "Narkoseversuche mit Hoheren Alkoholen und Stickstoffderivaten,
   Dissertation," Leube, F., Pharmakologischen Institut der Universitat
   Tubingen, Fed. Rep. Ger., 1931  Volume(issue)/page/year: -,-,1931

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   8,99,1947

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 umol/plate
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   40,1194,1980

系列性分类


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