Imiphos

CAS 1078-79-1 MFCD01706674

化学结构图

1078-79-1
SMILES: CC1SCCN1P(=O)(N1CC1)N1CC1

化学属性

Mol. FormulaC8H16N3OPS
Mol. Weight233.30

别名和识别编码

Chemical NamePhosphine oxide,bis(1-aziridinyl)(2-methyl-3-thiazolidinyl)-
Synonym Imiphos Marcophan Marcophane Markofane bis(1-aziridinyl)-2-methyl-3-thiazolidinyl phosphine oxide imifos imiphos
Wiswesser Line NotationT5N CSTJ B1 APO&- AT3NTJ&- AT3NTJ
Beilstein Registry Number1214283
CAS Number1078-79-1
PubChem Substance ID101962
InChIInChI=1S/C8H16N3OPS/c1-8-11(6-7-14-8)13(12,9-2-3-9)10-4-5-10/h8H,2-7H2,1H3
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安全信息

RTECSSY9625000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 142 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   21ACAB "Imifos," Giller, S.A., ed., Izd, Riga, USSR, 1968
   Volume(issue)/page/year: -,129,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 18700 ug/kg
TOXIC EFFECTS :
   Blood - leukopenia
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 37,464,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   21ACAB "Imifos," Giller, S.A., ed., Izd, Riga, USSR, 1968
   Volume(issue)/page/year: -,129,1968

系列性分类

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