Oxythiamine 化合物T12354

CAS 136-16-3 MFCD N/A

化学结构图

136-16-3
SMILES: [Cl-].Cl.CC1N=C(O)C(C[N+]2=CSC(CCO)=C2C)=CN=1

化学属性

Mol. FormulaC12H16N3O2S
Mol. Weight266.37

别名和识别编码

Chemical NameOxythiamine
Chemicalbook IDCB6428626
Wiswesser Line NotationT6N CNJ B1 DQ E1- AT5N CSJ D2Q E1
Synonym 5-(2-Hydroxyethyl)-3-((4-hydroxy-2-methyl-5-pyrimidinyl)methyl)-4-methyl-thiazolium Oxythiamine Oxythiamin
Beilstein Registry Number4153910
CAS Number136-16-3
Chemical Name Translation化合物T12354
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安全信息

RTECSXJ7050290
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1430 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 16,848,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 160 mg/kg
SEX/DURATION            : female 1-8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   FESTAS Fertility and Sterility.  (American Fertility Soc., 608 13th Ave. S,
   Birmingham, AL 35282) V.1-    1950-  Volume(issue)/page/year: 24,962,1973

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