Nifenazone Nifenazone

CAS 2139-47-1 MFCD00214069

化学结构图

2139-47-1
SMILES: Cc1c(NC(=O)c2cccnc2)c(=O)n(-c2ccccc2)n1C

化学属性

Mol. FormulaC17H16N4O2
Mol. Weight308

别名和识别编码

Chemical Nameanalytical standard Nifenazone
MDL NumberMFCD00214069
CAS Number2139-47-1
Synonym N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-pyridinecarboxamide Nicoron Anicotinoylantipyrine Nicodone Thylin Nicofesone 尼芬那宗 Nicotinamide, N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)- Nicotinic acid, amidophenyldimethylpyrazolone 4-(Nicotinoylamino)antipyrine 4-(Nicotinamido)antipyrine Nicophesone Nicoreumal N-Antipyrinylnicotinamide Nicazane Nikofezon Nicotinsaeureamidophenyldimethylpyrazolons Nicopyron Niapyrin 1,5-二甲基-4-烟酰胺-2-苯基-3-吡唑酮 4-Nicotinoylamido-1-phenyl-2,3-dimethyl-5-pyrazolone Nicophezon Nicotinoylaminoantipyrine Phenicazone Nicotinic acid 4-antipyrilamide Nicotazone Nifenazon Nicozone Nifenazone Nicodon Nikodon
PubChem Substance ID24897424
EC Number218-387-1
Chemical Name TranslationNifenazone
Wiswesser Line NotationT6NJ CVM- DT5NNVJ A1 BR& E1
Beilstein Registry Number0307504
LabNetwork Molecule IDLN00195878
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分类

  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, N, NA - NI, Neat Compounds, 分析/色谱
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, N, NA - NI, Neat Compounds

安全信息

RTECSQS4005000
WGK Germany2
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1280 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 9,132,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JDGRAX Journal of Drug Research.  (National Organization for Drug Research
   and Control, POB 29, Cairo, Egypt)  V.2-    1969-  Volume(issue)/page/year:
   4,89,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7890 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 12,235,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJPAAO Indian Journal of Pharmacy.  (Bombay, India)  V.1-40(1), 1939-78. For
   publisher information, see IJSIDW.  Volume(issue)/p

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Forensic and Veterinary Standards - Chromatography
  5. Drugs & Metabolites - Forensic and Veterinary Standards
  6. Neat Compounds - Drugs & Metabolites
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. N - Alphabetic
  5. NA - NI - N

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