1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 2'-甲氧基尿苷

CAS 2140-76-3 MFCD00056054

化学结构图

2140-76-3
SMILES: CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O

化学属性

Mol. FormulaC10H14N2O6
Mol. Weight258
Density1.422
TSCANo
Melting Point154-156

别名和识别编码

Chemical Name1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS Number2140-76-3
Synonym 2''-O-METHYLURIDINE CRYSTALLINE 2'-O-METHYLURIDINE 2'-O-METHYLURIDINE (CHIRAL) 2'-O-甲基尿苷 2'-o-Methyluridine 2'-甲氧基尿苷 O2'-Methyluridine
EC Number250-023-7
Beilstein Registry Number755710
MDL NumberMFCD00056054
Reaxys-RN755710
Chemical Name Translation2'-甲氧基尿苷
PubChem Substance ID102212
InChIInChI=1S/C10H14N2O6/c1-17-8-7(15)5(4-13)18-9(8)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1
LabNetwork Molecule IDLN01330365
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分类

  • {SNA} Alcohols, Building Blocks, C10, C9 to C10, C9 to C11, Carbonyl Compounds, Chemical Synthesis, Ethers, Heterocyclic Building Blocks, Organic Building Blocks, Oxygen Compounds, Pyrimidines, Ureas
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Carbohydrates & Derivatives

产品应用

  • Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.

相关文献及参考

  • Gratzner, H., et al.: Science, 218, 474

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
Storage condition 0-10 Store at 0°C 储存温度2-8℃ 0-10°C

其他信息

  • MOL 文件:2140-76-3.mol

系列性分类


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