2'-O-Methyladenosine 2'-甲氧基腺苷

CAS 2140-79-6 MFCD00056002

化学结构图

2140-79-6
SMILES: CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc21

化学属性

Mol. FormulaC11H15N5O4
Mol. Weight281.27
Density1.422
TSCANo
Melting Point200-202°C
Stability对热敏感
Boiling Point623.8°C at 760 mmHg
Flash Point331°C

别名和识别编码

Chemical Name2'-O-Methyladenosine
CAS Number2140-79-6
Synonym 2'-O-Methyladenosine {LY} 2'-O-Methyladenosine {} {LY} 2'-O-Methyladenosine {} {} {LY} 2'-O-Methyladenosine {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2'-O-Methyladenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2'-
EC Number250-023-7
Beilstein Registry Number42301
MDL NumberMFCD00056002
PubChem Substance ID102213
Reaxys-RN42301
Chemical Name Translation2'-甲氧基腺苷
LabNetwork Molecule IDLN00192894
InChIInChI=1S/C11H15N5O4/c1-19-8-7(18)5(2-17)20-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
Canonical SMILESO[C@H]1[C@@H](OC)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CO
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分类

  • Bases & Related Reagents
  • {SNA} Nucleoside Analogs, 核苷，核苷酸和寡核苷酸, 生化试剂
  • Nucleotides
  • Carbohydrates & Derivatives
  • Heterocycles
  • {SNA} Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides

产品应用

  • An analog of adenosine.

相关文献及参考

  • [2]. Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8.
  • Eldrup, A.B.
  • [1]. Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9.
  • [1]. Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9.
  • [2]. Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8.

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition -20°C, protect from light {LY} -20°C, protect from light <0°C <;0 {} {LY} -20°C, protect from light {} {} {LY} -20°C, protect from light {} {} {} {LY} -20°C, protect from light {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

  • 2'-O-Methyladenosine is an analog of adenosine used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.
  • Sigma Aldrich:2140-79-6(sigmaaldrich)
  • MOL 文件:2140-79-6.mol

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleoside Analogs - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleoside Analogs - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Synthetic Oligonucleotides and Related Reagents - Nucleosides, Nucleotides, Oligonucleotides
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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