4-Chlorobenzene-1,3-Diamine 4-氯-1,3-苯二胺

CAS 5131-60-2 MFCD00025284

化学结构图

5131-60-2
SMILES: Nc1ccc(Cl)c(N)c1

化学属性

Mol. FormulaC6H7ClN2
Mol. Weight142.59
Melting Point87-90°C
TSCAYes
Solubility<0.1 G/100 ML AT 19 ºC
Boiling Point298.6°C at 760 mmHg

别名和识别编码

Chemical Name4-Chlorobenzene-1,3-Diamine
Synonym 4-Chlorobenzene-1,3-diamine {LY} 4-Chlorobenzene-1,3-diamine {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,3-diamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlor
MDL NumberMFCD00025284
PubChem Substance ID87565793
CAS Number5131-60-2
EC Number225-877-9
Reaxys-RN2081090
Chemical Name Translation4-氯-1,3-苯二胺
Beilstein Registry Number2081090
Wiswesser Line NotationZR CZ DG
LabNetwork Molecule IDLN00240676
InChIInChI=1S/C6H7ClN2/c7-5-2-1-4(8)3-6(5)9/h1-3H,8-9H2
Canonical SMILESNC1=CC=C(Cl)C(N)=C1
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分类

  • {SNA} Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Polyamines
  • Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Polyamines

相关文献及参考

  • Beil. 13 ,53
  • IR-Spectra (3), 742:A / IR-Spectra (2), 652:G / NMR-Reference 2 (1), 1049:C

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P304+P340+P312
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes
RTECSSS8800000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
UN Number
Packing GroupIII
Hazard Class6.1
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 917 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-85,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7140 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Behavioral - somnolence (general depressed activity)
   Liver - tumors
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 27,81,1982

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3745 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 27,81,1982

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5460 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   IMEMDT IARC Monograph

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
   Toxicology of New Industrial Chemical Substances.  For English translation,
   see TNICS*.  (Izdatel'stvo Meditsina, Moscow, USSR)  No.1-    1961-
   Volume(issue)/page/year: 7,138,1965

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7(Suppl
   5),1,1985

Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • MSDS 信息:4-Chloro-1,3-phenylenediamine(5131-60-2).msds
  • 图谱信息:4-氯-1,3-苯二胺(5131-60-2)红外图谱(IR1) 4-氯-1,3-苯二胺(5131-60-2)质谱(MS) 4-氯-1,3-苯二胺(5131-60-2)红外图谱(IR2)
  • Alfa Aesar:4-氯间苯二胺,97% 4-Chloro-m-phenylenediamine, 97%(5131-60-2)
  • TCI Shanghai:4-氯-1,3-苯二胺 4-Chloro-1,3-phenylenediamine,>;98.0%(T)(5131-60-2)
  • 用途一:用于有机合成中间体
  • MOL 文件:5131-60-2.mol
  • Sigma Aldrich:5131-60-2(sigmaaldrich)
  • 4-氯-1,3-苯二胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0710 4-氯-1,3-苯二胺 4-Chloro-1,3-phenylenediamine 5G 836元 2014/06/02 C0710 4-氯-1,3-苯二胺 4-Chloro-1,3-phenylenediamine 25G 2460元 2010/05/25 A15430 4-氯间苯二胺, 97% 4-Chloro-m-phenylenediamine, 97% 5g 718元

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