Ethanol, 2-(isobutylamino)-, p-aminobenzoate (ester),monohydrochloride

CAS 553-68-4 MFCD N/A

化学结构图

553-68-4
SMILES:

化学属性

Mol. Weight272.81
Mol. FormulaC13H20N2O2.ClH

别名和识别编码

Wiswesser Line NotationZR DVO2M1Y1&1
Chemical NameButethamine
Synonym p-Aminobenzoic acid ester of 2-isobutylaminoethanol hydrochloric acid
CAS Number553-68-4
Chemicalbook IDCB81178188
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安全信息

RTECSKL4375000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 169 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,483,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 182 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ANESAV Anesthesiology.  (Lippincott/Harper, Journal Fulfillment Dept., 2350
   Virginia Ave., Hagerstown, MD 21740)  V.1-    1940- Volume(issue)/page/year:
   3,398,1942

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 449 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ANESAV Anesthesiology.  (Lippincott/Harper, Journal Fulfillment Dept., 2350
   Virginia Ave., Hagerstown, MD 21740)  V.1-    1940- Volume(issue)/page/year:
   3,398,1942

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excit

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