1-Methylcarbamoyldiazepam

CAS 5606-59-7 MFCD N/A

化学结构图

5606-59-7
SMILES: CNC(=O)[C@@H]1N=C(c2cc(Cl)ccc2NC1=O)c1ccccc1

化学属性

Mol. FormulaC17H14ClN3O2
Mol. Weight327.79

别名和识别编码

Chemical Name1-Methylcarbamoyldiazepam
Synonym 1-Methylcarbamoyldiazepam D-58M 7-Chloro-2,3-dihydro-N-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxamide
CAS Number5606-59-7
Beilstein Registry Number0690746
InChIKeyMTEDNDAJJUTGNN-UHFFFAOYSA-N
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安全信息

RTECSDE8747930 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 840 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TAKHAA Takeda Kenkyusho Ho.  Journal of the Takeda Research Laboratories.
   (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532,
   Japan)  V.29-    1970-  Volume(issue)/page/year: 29,134,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TAKHAA Takeda Kenkyusho Ho.  Journal of the Takeda Research Laboratories.
   (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532,
   Japan)  V.29-    1970-  Volume(issue)/page/year: 29,134,1970

系列性分类

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