7-Methoxy-1,2,3,4-tetrahydroacridin-9-amine 7-甲氧基-1,2,3,4-四氢吖啶-9-胺

CAS 5778-80-3 MFCD01237613

化学结构图

5778-80-3
SMILES: COc1ccc2nc3c(c(N)c2c1)CCCC3

化学属性

Mol. FormulaC14H16N2O
Mol. Weight228.32

别名和识别编码

Chemical Name7-Methoxy-1,2,3,4-tetrahydroacridin-9-amine
InChIKeyAPQPVVOYBLOJDY-UHFFFAOYSA-N
Synonym 7-Methoxytacrine 7-Meota 9-Amino-7-methoxy-1,2,3,4-tetrahydroakridin 1,2,3,4-Tetrahydro-7-methoxy-9-acridinamine 9-Amino-7-methoxy-1,2,3,4-tetrahydroacridine 9-Acridinamine, 1,2,3,4-tetrahydro-7-methoxy-
CAS Number5778-80-3
Beilstein Registry Number0477401
PubChem Substance ID119053
InChIInChI=1S/C14H16N2O/c1-17-9-6-7-13-11(8-9)14(15)10-4-2-3-5-12(10)16-13/h6-8H,2-5H2,1H3,(H2,15,16)
Chemical Name Translation7-甲氧基-1,2,3,4-四氢吖啶-9-胺
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

安全信息

RTECSAR9532200 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 258 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   15,126,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 753 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   15,126,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   15,126,1990

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 168 gm/kg/24W (Continuous)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 244331,1990

TYPE OF TEST            : Unscheduled DNA synthesis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 16800 mg/kg/24W (Continuous)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 244331,1990

系列性分类

相关产品推荐