1',2'-Dihydrorotenone 二氢鱼藤酮

CAS 6659-45-6 MFCD N/A

化学结构图

6659-45-6
SMILES:

化学属性

Mol. FormulaC23H24O6
Mol. Weight396.47

别名和识别编码

Chemical Name1',2'-Dihydrorotenone
Chemical Name Translation二氢鱼藤酮
Chemicalbook IDCB01369063
Synonym Dihydrorotenone Rotenone, dihydro-
CAS Number6659-45-6
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相关文献及参考

  • [1]. Zhang J, et al. The natural pesticide dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway. PLoS One. 2013 Jul 26;8(7):e69911.

安全信息

RTECSDJ2623100
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 42,364,1953

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   IECHAD Industrial and Engineering Chemistry.  (Washington, DC)  V.15-62,
   1923-70.  For publisher information, see CHMTBL.  Volume(issue)/page/year:
   29,429,1937

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IECHAD Industrial and Engineering Chemistry.  (Washington, DC)  V.15-62,
   1923-70.  For publisher information, see CHMTBL.  Volume(issue)/page/year:
   29,429,1937

系列性分类


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