Ketamine

CAS 6740-88-1 MFCD N/A

化学结构图

6740-88-1
SMILES: CNC1(c2ccccc2Cl)CCCCC1=O

化学属性

Mol. Weight237.75
Mol. FormulaC13H16ClNO

别名和识别编码

Chemical NameCyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-,(+-)-
Wiswesser Line NotationL6VTJ BM1 BR BG
Synonym 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone 2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone 2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone CI 581 CI-581 CI581 Calipsol Calypsol Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)- Kalipsol Ketalar Ketamine Ketamine Hydrochloride Ketanest Ketaset
Beilstein Registry Number2216965
CAS Number6740-88-1
PubChem Substance ID3821
InChIInChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3
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安全信息

RTECSGW1300000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 77 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   JZKEDZ Jitchuken Zenrinsho Kenkyuho.  Central Institute for Experimental
   Animals, Research Reports. (Jikken Dobutsu Chuo Kenkyusho, 1433 Nogawa,
   Takatsu-ku, Kawasaki 211, Japan)  V.1-    1975-  Volume(issue)/page/year:
   1,119,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJANAD British Journal of Anesthesia.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1923-  Volume(issue)/page/year:
   55,457,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Primate - monkey
DOSE                    : 1 mg/kg
SEX/DURATION            : female 23 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
   BJANAD British Journal of Anesthesia.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1923-  Volume(issue)/page/year:
   47,917,1975

Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H332 Harmful if inhaled 吸入有害
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P301+P317
  • P302+P352
  • P304+P312
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P317
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
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