4-Amino-N-(4,5-Dimethyloxazol-2-Yl)Benzenesulfonamide 4-氨基-N-(4,5-二甲基噁唑-2-基)苯磺酰胺

CAS 729-99-7 MFCD00005303

化学结构图

729-99-7
SMILES: Cc1nc(NS(=O)(=O)c2ccc(N)cc2)oc1C

化学属性

Mol. FormulaC11H13N3O3S
Mol. Weight267.33

别名和识别编码

Chemical Name4-Amino-N-(4,5-Dimethyloxazol-2-Yl)Benzenesulfonamide
CAS Number729-99-7
Synonym ######## 2-(p-Aminobenzenesulfonamido)-4,5-dimethyloxazole 2-(p-Aminobenzolsulfonamido)-4,5-dimethyloxazol 4,5-Dimethyl-2-sulfanilamidooxazole 4-Amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamide 4-amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamide Benzenesulfonamide, 4-amino-N-(4,5-dimethyl-2-oxazolyl)- Justamil N(sup 1)-(4,5-Dimethyl-2-oxazolyl)sulfanilamide N1-(4,5-dimethyloxazol-2-yl)sulfanilamide Nuprin Oxasulfa Oxazole, 2-(p-aminophenylsulfonylamino)-4,5-dimethyl- Sulfabutin Sulfadimethyloxazole Sulfamoxole Sulfamoxolum Sulfano Sulfavigor Sulfmidil Sulfono Sulfune Sulfuno Sulphamoxole Tardamid Tardamide benzenesulf
MDL NumberMFCD00005303
Beilstein Registry Number248434
EC Number211-982-7
PubChem Substance ID12894
Chemical Name Translation4-氨基-N-(4,5-二甲基噁唑-2-基)苯磺酰胺
Wiswesser Line NotationT5N COJ BMSWR DZ& D1 E1
LabNetwork Molecule IDLN01311768
InChIInChI=1S/C11H13N3O3S/c1-7-8(2)17-11(13-7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6H,12H2,1-2H3,(H,13,14)
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds
  • {uni_hamburg} no charge; oxygen heterocycle; nitrogen heterocycle; carbocycle; aromatic; 5ring; 6ring; 1fragment
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Antibiotics, Bacteriostatic, Chemical Structure, Chromatography, Clinical Standards, Principle, S, SN - SZ, Sulfonamides

产品应用

  • Silversulfadiazine and Sulfamoxol are common drugs in treatment of bacterial disease.

相关文献及参考

  • Jaiswal, P., et al.: Talanta, 17, 236 (1970),
  • Saxena, A., et al.: Prog. Drugs Res., 30, 221 (1986),
  • Short: IV/8A Title: Enthalpies of Fusion and Transition of Organic Compounds Author: Zhang, Z.-Y.; Frenkel, M.; March, K.N.; Wilhoit, R.C. Editor: Marsh, K.N. Source: Landolt-Börnstein, New Series Volume: IV/8A Year: 1995 Keyword: organic compounds; enthaly of fusion; melting point; phase transition ISBN: 3-540-58854-X ISBN: 978-3-540-58854-2 Internet Resource: DOI:10.1007/b55145 RefComment: VIII, 588 pages.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

WGK Germany2
RTECSWO9150000
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P333+P313
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Hazard Codes Xi
Risk Statements
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
{hazard_com

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,634,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 10,612,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >12500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,634,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1285 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 10,612,1960

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. S - Alphabetic
  5. SN - SZ - S

相关产品推荐