Morphinan-14-ol, 4,5-alpha-epoxy-3-methoxy-17-methyl-

CAS 7387-55-5 MFCD N/A

化学结构图

7387-55-5
SMILES: COc1ccc2c3c1OC1CCCC4(O)C(C2)N(C)CCC314

化学属性

Mol. Weight301.42
Mol. FormulaC18H23NO3

别名和识别编码

Chemical NameMorphinan-14-ol, 4,5-alpha-epoxy-3-methoxy-17-methyl-
Synonym 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-14-ol RAM-306
Beilstein Registry Number0623758
CAS Number7387-55-5
InChIKeyRTSADQCTRAIWTC-LTCOOKNTSA-N
PubChem Substance ID5492912
InChIInChI=1S/C18H23NO3/c1-19-9-8-17-14-4-3-7-18(17,20)13(19)10-11-5-6-12(21-2)16(22-14)15(11)17/h5-6,13-14,20H,3-4,7-10H2,1-2H3/t13-,14+,17-,18-/m1/s1
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安全信息

RTECSQD1707000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45600 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 84,268,1964

系列性分类

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