Streptamine,O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-

CAS 7542-37-2 MFCD00925606

化学结构图

7542-37-2
SMILES: NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CO)C(O)C(O)C3N)C2O)C(N)C(O)C1O

化学属性

Mol. FormulaC23H45N5O14
Mol. Weight615.73

别名和识别编码

Chemical NameStreptamine,O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-
Synonym Estomycin Paucimycin Monomycin A R 400 Crestomycin Quintomycin C Zygomycin A1 Antibiotic 503-3 Hydroxymycin Amminosidin Aminosidine I Neomycin E Paromomycine Paromomycin I Paromomycin Aminosidine Aminosidin Humycin Antibiotic 2230D Antibiotic SF 767B
CAS Number7542-37-2
Wiswesser Line NotationT6OTJ B1Z CQ DQ EZ FO- CT5OTJ B1Q DQ EO- CL6TJ AZ BQEZ DO- BT6OTJ CZ DQ EQ F1Q
Beilstein Registry Number0072285
PubChem Substance ID165580
InChIInChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
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安全信息

RTECSWK2315000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1010 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 12,243,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 930 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
   Tokyo, Univ. of Tokyo Press, 1967  Volume(issue)/page/year: -,

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 423 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PRMEAI Presse Medicale.  (Paris, France)  V.1-79n.55, 1893-1971.  For
   publisher information, see NPMDAD  Volume(issue)/page/year: 70,127,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 perce

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,674,1978

系列性分类

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