Tetrodotoxin, 4-amino-4-deoxy-, (4-alpha)-

CAS 7724-38-1 MFCD07724381

化学结构图

7724-38-1
SMILES: N=C1N[C@@H](N)[C@H]2[C@@H]3O[C@@]4(O)O[C@H]([C@@H]3O)[C@H](O)[C@]2(N1)[C@]4(O)CO

化学属性

Mol. Weight318.33
Mol. FormulaC11H18N4O7

别名和识别编码

Chemical NameTetrodotoxin, 4-amino-4-deoxy-, (4-alpha)-
Chemicalbook IDCB02264079
Synonym Tetrodaminotoxin
CAS Number7724-38-1
InChIKeyRZEZZMTUAUQGFF-UHFFFAOYSA-N
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安全信息

RTECSXF8881000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 477 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   3,58,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 26100 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JJPAAZ Japanese Journal of Pharmacology.  (Japanese Pharmacological Soc.,
   c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
   606, Japan)  V.1-    1951-  Volume(issue)/page/year: 17,267,1967

系列性分类

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