PERK

下级目录

7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine

CID 53469059

GDC-0879

G-573

PD-184352

目录项下的产品

1337531-36-8

1337531-36-8 / MFCD437531368
GSK2606414 is an orally available, potent, and selective PERK inhibitor. GSK2606414 inhibits PERK activation in cells and inhibits the growth of a human tumor xenograft in mice. Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states. Evidence that PERK is implicated in tumorigenesis and cancer cell survival stimulated our search for small molecule inhibitors.
1-(5-(4-氨基-7-甲基-7H-吡咯并[2,3-d]嘧啶-5-基)二氢吲哚-1-基)-2-(3-(三氟甲基)苯基)乙酮

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

1337532-29-2

1337532-29-2 / MFCD437532292
CID 53469059
1-(5-(4-氨基-7-甲基-7H-吡咯并[2,3-d]嘧啶-5-基)-4-氟吲哚啉-1-基)-2-(6-甲基吡啶-2-基)乙酮

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
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905281-76-7

905281-76-7 / MFCD005281767
(E)-5-(1-(2-hydroxyethyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,3-dihydroinden-1-one oxime
2,3-二氢-5-[1-(2-羟基乙基)-3-(4-吡啶基)-1H-吡唑-4-基]-1H-茚-1-酮肟

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
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22868-35-5

22868-35-5 / MFCD01438282
2-(3-Chlorophenyl)-1H-Benzo[D]Imidazole
2-(3-氯苯基)-1H-苯并[d]咪唑

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

212631-79-3

212631-79-3 / MFCD02683961
2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
2-[(2-氯-4-碘苯基)氨基]-N-(环丙基甲氧基)-3,4-二氟-苯甲酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
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