c-Myc

下级目录

(+)-JQ-1

BP-1-102

LOBAPLATIN

HA14-1

目录项下的产品

1268524-70-4

1268524-70-4 / MFCD368524704
(S)-Tert-Butyl 2-(4-(4-Chlorophenyl)-2,3,9-Trimethyl-6H-Thieno[3,2-f][1,2,4]Triazolo[4,3-a][1,4]Diazepin-6-yl)Acetate
(S)-(+)-2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩并[3,2-F][1,2,4]三唑并[4,3-A][1,4]二氮杂卓-6-基)乙酸叔丁酯

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国

1334493-07-0

1334493-07-0 / MFCD434493070
BP-1-102 is a potent, orally bioavailable and selective STAT3 inhibitor. BP-1-102 binds Stat3 with an affinity (K(D)) of 504 nM, blocks Stat3-phospho-tyrosine (pTyr) peptide interactions and Stat3 activation at 4-6.8 μM, and selectively inhibits growth, survival, migration, and invasion of Stat3-dependent tumor cells. BP-1-102-mediated inhibition of aberrantly active Stat3 in tumor cells suppresses the expression of c-Myc, Cyclin D1, Bcl-xL, Survivin, VEGF, and KrÃ¼ppel-like factor 8, which is identified as a Stat3 target gene that promotes Stat3-mediated breast tumor cell migration and invasion.
BP-1-102游离态

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

135558-11-1

135558-11-1 / MFCD35558111
Lobaplatin
乐铂

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

65673-63-4

65673-63-4 / MFCD00218213
ethyl (R)-2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
乙基-2-氨基-6-溴-4-(1-氰基-2-乙氧基-2-甲酰)-4H-苯并呋喃-3-羧酸

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

北京市
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