Estrogen/progestogen Receptor

下级目录

Brilanestrant

HJC-0123

CHF-4227

(E/Z)-4-Hydroxy Tamoxifen

GTX-758

Estriol

Pyrrolidine,1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)-, (E)-

Fulvestrant

目录项下的产品

1365888-06-7

1365888-06-7 / MFCD465888067
(E)-3-(4-((E)-2-(2-Chloro-4-Fluorophenyl)-1-(1H-Indazol-5-Yl)But-1-En-1-Yl)Phenyl)Acrylic Acid
(E)-3-(4-((E)-2-(2-氯-4-氟苯基)-1-(1H-吲唑-5-基)丁-1-烯-1-基)苯基)丙烯酸

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

1430420-02-2

1430420-02-2 / MFCD530420022
Downregulate phosphorylation of STAT3, increase the expression of cleaved caspase-3, inhibit cell cycle progression and promote apoptosis in breast and pancreatic cancer cells with low micromolar to nanomolar IC50 values. Furthermore, HJC-0123 significantly suppressed estrogen receptor (ER)-negative breast cancer MDA-MB-231 xenograft tumor growth in vivo (p.o.), indicating its great potential as an efficacious and orally bioavailable drug candidate for human cancer therapy.

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

444643-64-5

444643-64-5 / MFCD44643645
CHF-4227

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

68392-35-8

68392-35-8 / MFCD68392358
4-(1-(4-(2-(Dimethylamino)Ethoxy)Phenyl)-2-Phenylbut-1-En-1-Yl)Phenol
4-(1-(4-(2-(二甲基氨基)乙氧基)苯基)-2-苯基丁-1-烯-1-基)苯酚

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

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938067-78-8

938067-78-8 / MFCD038067788
GTX-758, also known as Capesaris, is a n orally available, nonsteroidal selective estrogen receptor (ER) alpha agonist with potential antineoplastic activity. Upon administration of GTx-758, this agent suppresses the secretion of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the pituitary gland through feedback inhibition. In males, the inhibition of LH secretion prevents the synthesis of androgens, including testosterone, by the testes. This may result in suppressed total serum testosterone to the levels observed in castration. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

50-27-1

50-27-1 / MFCD00003691
Estriol
雌三醇

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
北京市
√
山东省

116057-75-1

116057-75-1 / MFCD00865557
Pyrrolidine,1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)-, (E)-

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

129453-61-8

129453-61-8 / MFCD00903953
(7α,17β)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
(7α,17β)-7-[9-(4,4,5,5,5-五氟戊亚磺酰基)壬烷基]雌甾-1,3,5(10)-三烯-3,17-二醇

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
北京市
√

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