Aurora Kinase

下级目录

Alisertib

A-443654

Barasertib

AKI-001

CCT129202

AMG900

AZD1152-HQPA

目录项下的产品

1028486-01-2

1028486-01-2 / MFCD128486012
4-((9-Chloro-7-(2-Fluoro-6-Methoxyphenyl)-5H-Benzo[C]Pyrimido[4,5-E]Azepin-2-Yl)Amino)-2-Methoxybenzoic Acid
4-((9-氯-7-(2-氟-6-甲氧基苯基)-5H-苯并[c]嘧啶并[5,4-d]氮杂卓-2-基)氨基)-2-甲氧基苯甲酸

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
√

552325-16-3

552325-16-3 / MFCD52325163
A-443654

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

722543-31-9

722543-31-9 / MFCD22543319
2-(Ethyl(3-((4-((3-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-5-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyl dihydrogen phosphate
5-[[7-[3-[乙基[2-(磷酰氧基)乙基]氨基]丙氧基]-4-喹唑啉基]氨基]-N-(3-氟苯基)-1H-吡唑-3-乙酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

925218-37-7

925218-37-7 / MFCD025218377
AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Phenotypic cellular assays show that both Aurora A and Aurora B are inhibited at inhibitor concentrations sufficient to block proliferation. Importantly, the cellular activity translates to potent inhibition of tumor growth in vivo. An oral dose of 5 mg/kg QD is well tolerated and results in near stasis (92% TGI) in an HCT116 mouse xenograft model.

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

942947-93-5

942947-93-5 / MFCD042947935
CCT129202

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

945595-80-2

945595-80-2 / MFCD045595802
N-(4-((3-(2-Aminopyrimidin-4-Yl)Pyridin-2-Yl)Oxy)Phenyl)-4-(4-Methylthiophen-2-Yl)Phthalazin-1-Amine
N-(4-((3-(2-氨基嘧啶-4-基)吡啶-2-基氧基)苯基)-4-(4-甲基噻吩-2-基)酞嗪-1-胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

722544-51-6

722544-51-6 / MFCD10687152
3-[[7-[3-[Ethyl(2-Hydroxyethyl)Amino]Propoxy]-4-Quinazoline]Amino]-N-(3-Fluorophenyl)-1H-Pyrazole-3-Acetamide
5-[[7-[3-[乙基(2-羟基乙基)氨基]丙氧基]-4-喹唑啉]氨基]-N-(3-氟苯基)-1H-吡唑-3-乙酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
√

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