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Medical Research Areas
Microbiology
HIV Protease
HIV Protease
下级目录
Cobicistat
GSK2838232
Bromosporine
AMD 3465 hexahydrobromide
Boceprevir
Elvitegravir
Temsavir (BMS-626529)
Itmn-191 Danoprevir
MSX-122
Betulinic acid
Megestrol acetate
Miltefosine
Bevirimat
NIGERICIN
目录项下的产品
1004316-88-4 / MFCD104316884
Cobicistat
可比西他
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
中华人民共和国
√
1443461-21-9 / MFCD543461219
28-Norlup-18-en-21-one, 3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-, (3β)-
(3BETA)-3-(3-羧基-3-甲基-1-氧代丁氧基)-17-[(1R)-2-[[(3-氯苯基)甲基][2-(二甲基氨基)乙基]氨基]-1-羟基乙基]-28-去甲-18-羽扇烯-21-酮
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
中华人民共和国
1619994-69-2 / MFCD719994692
Bromosporine is a broad spectrum inhibitor for bromodomains and as such will be very useful in elucidating further biological roles of reader domains as well as a tool for the validation of functional assays. Proteins that contain BRDs have been implicated in the development of a large variety of diseases, including various cancers, inflammatory diseases and neurological diseases and the therapeutic potential of bromodomain inhibition has been shown in several of these diseases, such as HIV, cancer and inflammation.
(3-甲基-6-(4-甲基-3-(甲基磺酰胺基)苯基)-[1,2,4]三唑并[4,3-b]哒嗪-8-基)氨基甲酸乙酯
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
中华人民共和国
185991-07-5 / MFCD85991075
AMD3465 is a novel CXCR4 receptor antagonist with potential anticancer and anti-HIV activity. AMD3465 can block infection of T-tropic, CXCR4-using HIV.
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
中华人民共和国
394730-60-0 / MFCD94730600
Boceprevir
波普瑞韦
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
中华人民共和国
697761-98-1 / MFCD97761981
Elvitegravir
埃替拉韦
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
中华人民共和国
√
701213-36-7 / MFCD01213367
Temsavir, also known as BMS-626529, is a potent HIV-1 attachment inhibitor. BMS-663068 is also the phosphonooxymethyl prodrug of BMS-626529 that targets HIV-1 gp120 and prevents its binding to CD4(+) T cells. BMS-626529 had half-maximal effective concentration (EC(50)) values of <10 nM against the vast majority of viral isolates; however, susceptibility varied by >6 log(10), with half-maximal effective concentration values in the low pM range against the most susceptible viruses.
1-(4-苯甲酰基哌嗪-1-基)-2-(-甲氧基-7-(3-甲基-1H-1,2,4-三唑-1-基)-1H-吡咯并[2,3-C]吡啶-3-基)乙烷-1,2-二酮
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
850876-88-9 / MFCD50876889
Danoprevir, also known as ITMN-191 and RG-7227, is under development by InterMune Inc and Roche Holding AG, is a promising, potent NS3/4A protease inhibitor for the oral treatment of HCV infection. Preclinical data demonstrated that danoprevir binds with high affinity and dissociates slowly from the HCV NS3 protease, allowing high liver drug exposure with only modest plasma drug exposure. A phase Ib, 'IFN-free' clinical trial demonstrated that danoprevir, combined with the HCV polymerase inhibitor RG-7128 (Pharmasset Inc/Roche Holding AG), was effective in reducing HCV-RNA levels in a large proportion of treatment-naïve patients with HCV infection and in approximately half of previously non-responsive patients with HCV-1 infection, without resistance or safety concerns.
丹诺普韦
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
897657-95-3 / MFCD97657953
N,N"-(1,4-Phenylenebis(methylene))bis(pyrimidin-2-amine)
N,N"-(1,4-亚苯基双(亚甲基))双(嘧啶-2-胺)
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
472-15-1 / MFCD00009619
Betulinic Acid
桦木酸
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
中华人民共和国
√
595-33-5 / MFCD00056470
Megestrol Acetate
醋酸孕甾酮
原料
0 #
资源
0.0
询
0.0
%成交
交易量
试剂
中华人民共和国
北京市
√
58066-85-6 / MFCD00133396
hexadecyl (2-(trimethylammonio)ethyl) phosphate
米替福新
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
√
174022-42-5 / MFCD00954243
Bevirimat
贝韦立马
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂
28380-24-7 / MFCD01941536
Nigericin Sodium Salt
尼日利亚菌素
原料
0
资源
0.0
询
0.0
%成交
交易量
试剂