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分类

• Biochemicals and Reagents, Cell Biology, Cell Lysis Reagents, Cell Signaling and Neuroscience, Enzymatic Cell Lysis and Protoplast Preparation, Enzymes, Enzymes, Inhibitors, and Substrates, Hemolysin, Mammalian, Plasma & Blood Proteins, Plasma, Blood, and Related Proteins and Reagents, Proteins and Derivatives, Signal Transduction Research Tools
• {SNA} Cell Lysis Reagents, Cell Lysis Reagents Enzymes, Enzymatic Cell Lysis and Protoplast Preparation, Hemolysin, Mammalian, Plasma & Blood Proteins, Plasma, Blood, and Related Proteins and Reagents, Signal Transduction Research Tools, 生化试剂, 细胞信号转导和神经科学,

相关文献及参考

• Thelestam, M., and Blomqvist, L., Staphylococcal alpha toxin--recent advances. Toxicon 26 , 55-65, (1988) 摘要
• Fink, D., et al., Staphylococcus aureus alpha-toxin activates phospholipases and induces a Ca 2+ influx in PC12 cells. Cell. Signal. 1 , 387-393, (1989) 摘要
• Digby, G.J., et al., Differential dissociation of G protein heterotrimers. J. Phys. Chem. 586 , 3325-35, (2008) 摘要
• Muñoz-Planillo, R., et al., A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J. Histochem. Cytochem. 183 , 3942-8, (2009) 摘要
• Kayed, R., et al., Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer. J. Bacteriol. 284 , 4230-7, (2009) 摘要

安全信息

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BBACAQ Biochimica et Biophysica Acta.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1947- Volume(issue)/page/year:
   535,388,1978

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36670 ng/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 23,801,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 13,129,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 10,119,1972

GHS Symbol