CHPG

CAS 170846-74-9 MFCD01321059

化学结构图

170846-74-9
SMILES: NC(C1C=C(O)C=CC=1Cl)C(O)=O

化学属性

Mol. FormulaC8H8ClNO3
Mol. Weight201.61

别名和识别编码

Chemical NameCHPG
Synonym α-amino-2-chloro-5-hydroxybenzeneacetic acid (RS)-2-chloro-5-hydroxyphenylglycine α-amino-2-chloro-5-hydroxybenzeneacetic acid CHPG α-amino-2-chloro-5-hydroxybenzeneacetic acid (RS)-2-chloro-5-hydroxyphenylglycine α-amino-2-chloro-5-hydroxybenzeneacetic acid
MDL NumberMFCD01321059
PubChem Substance ID329775148
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分类

  • {SNA} Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Neuroscience, Neurotransmission, Neurotransmitter Receptors
  • {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Neuroscience, Neurotransmission, Neurotransmitter Receptors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Chen T, et al. The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway. Int J Mol Med. 2012 Apr;29(4):630-6.
  • [1]. Qiu JL, et al. The selective mGluR5 agonist CHPG attenuates SO 2 -induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. Neurochem Int. 2015 Jun-Jul;85-86:46-52.
  • [1]. Qiu JL, et al. The selective mGluR5 agonist CHPG attenuates SO 2 -induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. Neurochem Int. 2015 Jun-Jul;85-86:46-52.
  • [2]. Chen T, et al. The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway. Int J Mol Med. 2012 Apr;29(4):630-6.

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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