GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE) TETRALITHIUM SALT
CAS 94825-44-2 MFCD00135151
化学结构图
SMILES: [Li+].[Li+].[Li+].[Li+].NC1NC(=O)C2N=CN([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O)C=2N=1
化学属性
| Mol. Formula | C10H12Li4N5O13P3S |
|---|---|
| Mol. Weight | 562.98 |
别名和识别编码
| Chemical Name | Guanosine 5'-[γ-thio]triphosphate tetralithium salt |
|---|---|
| Synonym | GTPγS tetralithium salt GTPγS tetralithium salt GTP-γ-S-Li4 Guanosine 5′-O-(3-thiotriphosphate) tetralithium salt GTPγS tetralithium salt GTP-γ-S-Li4 Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt GTP-γ-S-Li4 Guanosine 5′-O-(3-thiotriphosphate) tetralithium salt Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt |
| CAS Number | 94825-44-2 |
| PubChem Substance ID | 24895344 |
| EC Number | 305-606-1 |
| Beilstein Registry Number | 8182249 |
| MDL Number | MFCD00135151 |
| Chemical Name Translation |
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分类
- Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, G, G Protein Function, G Proteins and Cyclic Nucleotides, Reagents
- {SNA} Bioactive Small Molecule Alphabetical Index, G, G Protein Function, G Proteins and Cyclic Nucleotides, Reagents, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, G, G Protein Function, G Proteins and Cyclic Nucleotides, Reagents
相关文献及参考
- Marino, S.F., High-level Production And Characterization Of A G-protein Coupled Receptor Signaling Complex. FASEB J. 276 , 4515-28, (2009) 摘要
- Sánchez-Blázquez, P., et al., Brain-specific Galphaz Interacts With Src Tyrosine Kinase To Regulate Mu-opioid Receptor-NMDAR Signaling Pathway. Cell Physiol. Biochem. 21 , 1444-54, (2009)
- Gilman, A.G, G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56 , 615-649, (1987)
- Desrosiers, R.R, et al., Guanine nucleotides protect Rho proteins from endogenous proteolytic degradation in renal membranes. Biochem. Cell Biol. 76 , 63-72, (1998) 摘要
- Standaert, M., et al., Comparative effects of GTP-γ-S and insulin on the activation of phophosphatidylinositol 3-kinase and protein kinase N in rat adipocytes. J. Biol. Chem. 273 , 7470-7477, (1998)
- Elmendorf, J.S., et al., Guanosine 5'-O-(3-thiotriphosphate) (GTP-γ-S) stimulation of GLUT4 translocation is tyrosine kinase-dependent. J. Biol. Chem. 273 , 13289-13296, (1998)
- Hodson, E.A., Regulation of phospholipase C-δ by GTP-binding proteins-rhoA as an inhibitory modulator. Biochim. Biophys. Acta 1403 , 97-101, (1998) 摘要
- Li, L., et al., Activation of phospholipase D by ADP-ribosylation factor in rat submandibular acinar cells. Arch. Oral Biol. 43 , 211-219, (1998) 摘要
- Katanaev, V.L., and Wymann, M.P., GTP-γ-S-induced actin polymerisation in vitro : ATP- and phosphoinositide-independent signalling via Rho-family proteins. J. Cell Sci. 111 , 1583-1599, (1998)
安全信息
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
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