o-Nicotine

CAS 23950-04-1 MFCD01691589

化学结构图

23950-04-1
SMILES: CN1CCCC1C1=CC=CC=N1

化学属性

Mol. FormulaC10H14N2
Mol. Weight162.26

别名和识别编码

Chemical NamePyridine, 2-(1-methyl-2-pyrrolidinyl)-
CAS Number23950-04-1
Synonym ortho-Nicotine alpha-Nicotine 2-(1-Methyl-2-pyrrolidinyl)pyridine alpha-Pyridyl-alpha-methylpyrrolidine
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Aromatics
  • Neurochemicals
  • Nicotine Derivatives
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • o-Nicotine is a Nicotine analog (N412420). o-Nicotine has high affinity for nicotinic receptor, and its ability to elicit neurotransmitter secretions make it a good candidate for treating cholinergic

相关文献及参考

  • Romano, C., et al.: Psychopharmacol., 74, 310 (1981),
  • Wang, D., et al.: Drug Dev. Res., 45, 10 (1998),

安全信息

Restrict 剧毒化学品
RTECSUT5809000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,584,1948

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,584,1948

系列性分类

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