Phosphonamidic acid,p-(1-aziridinyl)-N-(2-nicotinoylethyl)-, p-phenyleneester

CAS 40951-24-4 MFCD01706394

化学结构图

40951-24-4
SMILES: O=C(CCNP(=O)(OC1C=CC(=CC=1)OP(=O)(NCCC(=O)C1=CN=CC=C1)N1CC1)N1CC1)C1C=NC=CC=1

化学属性

Mol. FormulaC26H30N6O6P2
Mol. Weight584.56

别名和识别编码

Chemical NamePhosphonamidic acid,p-(1-aziridinyl)-N-(2-nicotinoylethyl)-, p-phenyleneester
Synonym A-273 p-(1-Aziridinyl)-N-(2-nicotinoylethyl)phosphonamidic acid p-phenylene
CAS Number40951-24-4
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安全信息

RTECSSZ6187000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - hypermotility, diarrhea
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   FATOBP Farmakologiya i Toksikologiya (Kiev).  Pharmacology and Toxicology.
   (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii,
   Kiev, USSR)  No.1-    1964-  Volume(issue)/page/year: 6,145,1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - hypermotility, diarrhea
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   FATOBP Farmakologiya i Toksikologiya (Kiev).  Pharmacology and Toxicology.
   (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii,
   Kiev, USSR)  No.1-    1964-  Volume(issue)/page/year: 6,145,1971

系列性分类

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