R-(-)-α-3-(1-萘氧基)-1,2-环氧丙烷 R-(-)-α-3-(1-萘氧基)-1,2-环氧丙烷

CAS 56715-28-7 MFCD01709480

化学结构图

56715-28-7
SMILES: C1OC1COC1=CC=CC2=CC=CC=C21

化学属性

Mol. FormulaC13H12O2
Mol. Weight200.25

别名和识别编码

Chemical NameOxirane, ((1-naphthalenyloxy)methyl)-, (R)-
CAS Number56715-28-7
Synonym (2R)- (R)-((1-Naphthalenyloxy)methyl)oxirane (R)-(-)-Glycidyl 1-naphthyl ether
Chemical Name TranslationR-(-)-α-3-(1-萘氧基)-1,2-环氧丙烷
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分类

  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Intermediates,

产品应用

  • Used in the preparation of Naftopidil (N213500) enantiomers.

相关文献及参考

  • Erhard, P., et al.: J. Med. Chem., 25, 1402

安全信息

RTECSRR0580000 
TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,197,1993

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,197,1993

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 nmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,197,1993

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,197,1993

系列性分类

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