2H-1,3,2-Oxazaphosphorin-2-amine,tetrahydro-3-(2-bromoethyl)-N-(2-chloroethyl)-,2-oxide, (+-)-

CAS 146367-82-0 MFCD01710220

化学结构图

146367-82-0
SMILES: O=P1(NCCCl)OCCCN1CCBr

化学属性

Mol. FormulaC7H15BrClN2O2P
Mol. Weight305.57

别名和识别编码

Chemical Name2H-1,3,2-Oxazaphosphorin-2-amine,tetrahydro-3-(2-bromoethyl)-N-(2-chloroethyl)-,2-oxide, (+-)-
Synonym Chlorobromofosfamide
CAS Number146367-82-0
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安全信息

RTECSRP5788699 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 566 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IITOEF Immunopharmacology and Immunotoxicology.  (Marcel Dekker, 270 Madison
   Ave., New York, NY  10016)  V.9-    1987-  Volume(issue)/page/year:
   14,883,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 334 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IITOEF Immunopharmacology and Immunotoxicology.  (Marcel Dekker, 270 Madison
   Ave., New York, NY  10016)  V.9-    1987-  Volume(issue)/page/year:
   14,883,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 361 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IITOEF Immunopharmacology and Immunotoxicology.  (Marcel Dekker, 270 Madison
   Ave., New York, NY  10016)  V.9-    1987-  Volume(issue)/page/year:
   14,883,1992

系列性分类

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