1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol, 8-allyl-,(+-)-

CAS 22235-85-4 MFCD01711248

化学结构图

22235-85-4
SMILES: C=CCN1[C@@H]2C[C@@H](O)C[C@H]1CC2 |&1:4,6,9|

化学属性

Mol. FormulaC10H17NO
Mol. Weight167.28

别名和识别编码

Chemical Name1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol, 8-allyl-,(+-)-
Synonym Noratropine, N-allyl- N-Allylnoratropine Naltropine
Wiswesser Line NotationT56 A ANTJ A2U1 GQ
CAS Number22235-85-4
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安全信息

RTECSRD1225000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 165 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 154,210,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 13,567,1963

系列性分类


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