1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol,6-beta,7-beta-epoxy-, (-)-tropate, hydrochloride

CAS 24676-80-0 MFCD01711257

化学结构图

24676-80-0
SMILES: Cl.OC[C@@H](C(=O)O[C@H]1C[C@@H]2N[C@H](C1)[C@H]1O[C@H]12)C1C=CC=CC=1

化学属性

Mol. FormulaC16H19NO4.ClH
Mol. Weight325.82

别名和识别编码

Chemical Name1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol,6-beta,7-beta-epoxy-, (-)-tropate, hydrochloride
Synonym Norscopolamine hydrochloride
CAS Number24676-80-0
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安全信息

RTECSRD1575000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraduodenal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 860 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 180,155,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3020 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 180,155,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4230 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 180,155,1969

系列性分类

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