Morpholine,4-isopropyl-2-(alpha,alpha,alpha-trifluoro-m-tolyl)-,hydrochloride

CAS 26629-86-7 MFCD01713669

化学结构图

26629-86-7
SMILES: Cl.CC(C)N1CCOC(C1)C1C=CC=C(C=1)C(F)(F)F

化学属性

Mol. FormulaC14H18F3NO.ClH
Mol. Weight309.79

别名和识别编码

Chemical NameMorpholine,4-isopropyl-2-(alpha,alpha,alpha-trifluoro-m-tolyl)-,hydrochloride
Synonym Conflictan 4-Isopropyl-2-(alpha,alpha,alpha-trifluoro-m-tolyl)morpholine CERM-1766
CAS Number26629-86-7
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安全信息

RTECSQE5270000
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - child
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Sense Organs and Special Senses (Eye) - increased intraocular pressure
   Behavioral - coma
REFERENCE :
   JTCTDW Journal of Toxicology, Clinical Toxicology.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.19-    1982-  Volume(issue)/page/year:
   30,123,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 365 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3637680

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 29,81,1974

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 30,539,1975

系列性分类


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