Ethanol, 2,2'-((4,5-diphenyl-2-oxazolyl)imino)di-,monohydrate

CAS 63867-52-7 MFCD01727934

化学结构图

63867-52-7
SMILES: O.OCCN(CCO)C1=NC(=C(O1)C1C=CC=CC=1)C1C=CC=CC=1

化学属性

Mol. FormulaC19H20N2O3.H2O
Mol. Weight342.43

别名和识别编码

Chemical NameEthanol, 2,2'-((4,5-diphenyl-2-oxazolyl)imino)di-,monohydrate
Synonym 2,2'-((4,5-Diphenyl-2-oxazolyl)imino)-diethanol monohydrate 2-(Bis(beta-hydroxyethyl)amino)-4,5-diphenyloxazole monohydrate Ditazol monohydrate Diethamphenazol monohydrate Ageroplas S 222 2,2'-Dihydroxy-N-(4,5-diphenyloxazole-2-yl)diethylamine monohydrate N-(4,5-Diphenyloxazol-2-yl)diethanolamine monohydrate
Wiswesser Line NotationT5N COJ BN2Q2Q DR& ER &QH
CAS Number63867-52-7
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安全信息

RTECSKK7400000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 11380 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1283,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7770 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1283,1973

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2300 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,1092,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3390 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research

系列性分类

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