Ergoline-8-propionamide, 6-allyl-alpha-cyano-,(8-beta)-

CAS 74627-37-5 MFCD01729241

化学结构图

74627-37-5
SMILES: C=CCN1C[C@H](CC(C#N)C(N)=O)C[C@H]2[C@H]1CC1=CNC3=CC=CC2=C13

化学属性

Mol. FormulaC21H24N4O
Mol. Weight348.49

别名和识别编码

Chemical NameErgoline-8-propionamide, 6-allyl-alpha-cyano-,(8-beta)-
Synonym 6-Allyl-alpha-cyanoergoline-8-propionamide 6-Allyl-alpha-cyanoergoline-8-beta-propionamide Ergoline-8-propanamide, alpha-cyano-6-(2-propenyl)-, (8-beta)-
CAS Number74627-37-5
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安全信息

RTECSKE6345020 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 33,1094,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 300 ug/kg
SEX/DURATION            : female 5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 33,1094,1983

系列性分类

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