Curcumenol 莪术烯醇

CAS 19431-84-6 MFCD01729508

化学结构图

19431-84-6
SMILES: CC(C)=C1C[C@@]23O[C@]1(O)C=C(C)[C@@H]2CC[C@@H]3C

化学属性

Mol. FormulaC15H22O2
Mol. Weight234.37
Density1.10

别名和识别编码

Chemical NameCurcumenol
Synonym (+)-Curcumenol 5-beta-Guiaia-7(11),9-dien-8-alpha-ol, 5,8-epoxy- (3S,3alphaS,6R,8alphaS)-1,2,3,4,5,8alpha-Hexahydro-3,8-dimethyl-5-(1-methylethylidene)-6H-3alpha,6-epoxyazulen-6-ol Curcumenol
CAS Number19431-84-6
Beilstein Registry Number3094585
Chemical Name Translation莪术烯醇
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相关文献及参考

  • [2]. Lo JY, et al. Curcumenol isolated from Curcuma zedoaria suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells. Food Funct. 2015 Nov;6(11):3550-9.
  • [1]. Sun DX, et al. Inhibitory effects of curcumenol on human liver cytochrome P450 enzymes. Phytother Res. 2010 Aug;24(8):1213-6.
  • [1]. Sun DX, et al. Inhibitory effects of curcumenol on human liver cytochrome P450 enzymes. Phytother Res. 2010 Aug;24(8):1213-6.
  • [2]. Lo JY, et al. Curcumenol isolated from Curcuma zedoaria suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells. Food Funct. 2015 Nov;6(11):3550-9.

安全信息

RTECSKC5020000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PEAG "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai
   Science/Technology Publisher, Peop. Rep. China, 1994
   Volume(issue)/page/year: -,178,1994

系列性分类


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