Adenine, N-methyl-N-nitroso-

CAS 21928-82-5 MFCD01741326

化学结构图

21928-82-5
SMILES: CN(N=O)C1NC=NC2=NC=NC=12

化学属性

Mol. FormulaC6H6N6O
Mol. Weight178.18

别名和识别编码

Chemical NameAdenine, N-methyl-N-nitroso-
Wiswesser Line NotationT56 BN DM FN HNJ IN1&NO
Synonym 6-Mna N-Methyl-N-nitrosoadenine 1H-Purin-6-amine, N(sup 6)-methyl-N(sup 6)-nitroso- 6-(Methylnitrosamino)purine 1H-Purin-6-amine, N-methyl-N-nitroso- N-Methyl-N-nitroso-1H-purin-6-amine
CAS Number21928-82-5
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安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10263 mg/kg/72W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   IJCNAW International Journal of Cancer.  (International Union Against
   Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland)  V.1-    1966-
   Volume(issue)/page/year: 24,319,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15 gm/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   IAPUDO IARC Publications.  (WHO Publications Centre USA, 49 Sheridan Ave.,
   Albany, NY 12210) No.27-    1979-  Volume(issue)/page/year: 31,787,1980

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 485 gm/kg/34W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 18,79,1977

RTECSAU6560000

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